![]() two in skeletal muscle and one in cardiac muscle. Troponin-I subunit exists in three isoforms. The clinical pharmacist checks her international normalized ratio (INR) with a point-of-care (POC) device to monitor her anticoagulant therapy (warfarin). Troponin is the contraction regulating protein complex of striated muscle and consists of three distinct proteins: Troponin-I, Troponin-C, and Troponin-T. This device was concluded to have potential for providing faster results and relatively acceptable values to clinicians in need of immediate results. Performed at authorized locations by point of care operators. A very high correlation was observed in glucose, blood urea nitrogen and creatinine ( R>0.975), high correlation was observed in sodium, potassium, Hct and Hb ( R>0.9), and relatively good correlation was observed in chloride and total carbon dioxide ( R>0.7) compared to the central laboratory analysers.Ĭonclusions: i-STAT showed relatively high precision and linearity, and comparable data to that of routine hematology and chemistry analysers. In the aspect of linearity, the correlation coefficient values of all analytes were over 0.975 in the clinically important concentration range. Results: The coefficient of variation values for the within-run precision and total precision at 3 levels of all analytes were within 5%, except those for low level creatinine. i-STAT (Abbott Point of Care, Inc. Twelve studies reported diagnostic accuracy for estimated glomerular filtration rates half were rated as being at low risk of bias, but there were applicability concerns for most. Comparisons with a central laboratory hematology analyser, Coulter LH 780 (Beckman Coulter Inc., USA), and a chemical analyser, UniCel DxC 880i (Beckman Coulter Inc.), were performed using 85 patient samples according to CLSI EP9-A3. Fifty-four studies were included in the clinical reviews. Methods: The precision and linearity of the 10 analytes were measured according to Clinical and Laboratory Standards Institute (CLSI) EP15-A3 and EP6-A guidelines. Radiometer ABL800 Flex, Ortho Vitros Fusion 5.1, Advanced Instruments Osmometer, Sebia Hydrasys 2 Scan, POC - i-STAT Molecular: cobas Liat PCR System. ![]() Therefore, the aim of this study was to evaluate the performance of the i-STAT POC analyser (Abbott Diagnostics, USA) for testing 8 chemical analytes (viz., sodium, potassium, chloride, total carbon dioxide, blood urea nitrogen, creatinine, glucose, and ionised calcium) and 2 hematological analytes (hematocrit, hemoglobin ). ![]() The demand for POCT in the medical field is expanding significantly, given that rapid results can eventually lead to early diagnosis and immediate clinical management of diseases. Background: Point-of-care testing (POCT) is designed to be used near the site where the clinical care is being delivered. ![]()
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